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Stillwater BioLabs
GH-Axis Receptor Research

CJC-1295 + Ipamorelin Blend

What's in the vial:5mgCJC-1295 (no DAC)+5mgIpamorelin
$75

A lyophilized blend combining CJC-1295 no DAC (30 aa, 3367.97 g/mol) and Ipamorelin (5 aa, 711.85 g/mol) for in-vitro receptor co-activation studies.

$75

1 vial Γ— $75 each

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Third-party tested

For laboratory research use only. Not for human or veterinary use. Not for diagnostic or therapeutic use.

Supplied to qualified labs and institutional buyers. Institutional use & buyer eligibility

Characteristics

Characteristics of CJC-1295 + Ipamorelin Blend
PropertyValue
ComponentsCJC-1295 no DAC (Mod GRF 1-29) + Ipamorelin
CJC-1295 Molecular FormulaC₁₅₂Hβ‚‚β‚…β‚‚Nβ‚„β‚„Oβ‚„β‚‚
Ipamorelin Molecular FormulaCβ‚ƒβ‚ˆH₄₉N₉Oβ‚…
CJC-1295 Molar Mass3367.97 g/mol
Ipamorelin Molar Mass711.85 g/mol
Physical FormLyophilized powder blend
SolubilityBoth components soluble in aqueous laboratory solvent
Organoleptic ProfileWhite lyophilized powder; odorless
Storage ConditionsStore lyophilized at -20Β°C; reconstituted solution stable at 2-8Β°C for up to 21 days
CompositionLyophilized blend of Modified GRF (1-29) acetate and Ipamorelin acetate

How is CJC-1295 + Ipamorelin Blend Used in Research?

The CJC-1295 no DAC + Ipamorelin blend is a lyophilized research formulation combining a 30-amino acid GHRH analog (3367.97 g/mol) with a 5-amino acid synthetic pentapeptide (711.85 g/mol) for in-vitro receptor co-activation studies. The blend is supplied as a laboratory research standard targeting GHRH-R and GHS-R1a binding assays in parallel. Not for use in any living organism.

Characterization workflows profile the blend in recombinant GHRH-R and GHS-R1a expression systems, with standard biochemical readouts including cAMP accumulation (Gs-cAMP-PKA pathway) and IP1/calcium-flux panels (Gq/11-PLC-calcium pathway). In cultured pituitary somatotroph cell lines, the two components can be co-applied to study convergent signaling from the two receptor systems.

Researchers use this blend as a combined reference mixture for analytical method development (HPLC/LC-MS comparability assays requiring simultaneous quantitation of both peptides) and as a two-receptor co-activation reference for functional characterization of novel GHRH or GHS analogs.

This product is supplied in a lyophilized form and requires reconstitution prior to laboratory handling. For research and laboratory use only. Not for human or veterinary consumption.

Areas of Study

Two-Receptor In-Vitro Co-Activation Studies

Applied as a combined reference mixture for parallel GHRH-R and GHS-R1a binding and functional readouts in recombinant cell systems.

Convergent Signaling Characterization

Used to profile Gs-cAMP-PKA versus Gq/11-PLC-calcium pathway readouts simultaneously in cultured somatotroph cell lines.

Receptor Selectivity Profiling

Applied in multi-receptor panels to profile each component's selectivity signature within the two-component blend.

Analytical Method Development

Serves as a combined identity, purity, and potency reference standard in HPLC and LC-MS comparability workflows.

Structural Characterization

Used in mass-spectrometry and circular-dichroism profiling of the two-component lyophilized reference standard.

References

  1. [1]Bowers CY, Granda R, Mohan S, et al. (2004). Sustained elevation of pulsatile growth hormone (GH) secretion and insulin-like growth factor I (IGF-I) by a combination of the GH-releasing peptide-6 and GH-releasing hormone. Journal of Clinical Endocrinology & Metabolism, 89(10), 5174-5181.
  2. [2]Raun K, Hansen BS, Johansen NL, et al. (1998). Ipamorelin, the first selective growth hormone secretagogue. European Journal of Endocrinology, 139(5), 552-561.
  3. [3]Ionescu M, Frohman LA. (2006). Pulsatile secretion of growth hormone (GH) persists during continuous stimulation by CJC-1295, a long-acting GH-releasing hormone analog. Journal of Clinical Endocrinology & Metabolism, 91(12), 4792-4797.
  4. [4]Veldhuis JD, Keenan DM, Bailey JN, et al. (2008). Novel relationships of age, visceral adiposity, insulin-like growth factor (IGF)-I and IGF binding protein concentrations to growth hormone (GH) releasing-hormone and GH releasing-peptide efficacies in men during experimental hypogonadal clamp. Journal of Clinical Endocrinology & Metabolism, 93(6), 2143-2150.

Disclaimer: The information provided is for research reference only and does not constitute medical advice. Products are sold strictly for in-vitro research use.

Certificate of Analysis (COA)

Third-Party Verified Quality

Every batch of CJC-1295 + Ipamorelin Blendis independently tested by an A2LA-accredited (ISO 17025:2017) third-party laboratory using HPLC-UV/VIS for purity and measured quantity. Each COA carries the lab's signed report and a batch-specific lot number. We publish these results publicly so you can verify exactly what you're getting.

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